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CAS 85-83-6 | Sudan IV

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Common Name	Sudan IV
CAS Number	85-83-6	Molecular Weight	380.442
Density	1.2±0.1 g/cm3	Boiling Point	618.8±55.0 °C at 760 mmHg
Molecular Formula	C₂₄H₂₀N₄O	Melting Point	199ºC
MSDS	ChineseUSA	Flash Point	424.4±20.8 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	sudan IV
Synonym	More Synonyms

Sudan IV BiologicalActivity

Description	Sudan IV is a lysochrome (fat-soluble dye) diazo dye used for the staining of lipids, triglycerides and lipoproteins on frozen paraffin sections[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Refat NA, et al. The induction of cytochrome P450 1A1 by sudan dyes. J Biochem Mol Toxicol. 2008 Mar-Apr;22(2):77-84.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	618.8±55.0 °C at 760 mmHg
Melting Point	199ºC
Molecular Formula	C₂₄H₂₀N₄O
Molecular Weight	380.442
Flash Point	424.4±20.8 °C
Exact Mass	380.163696
PSA	69.67000
LogP	6.66
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.645
InChIKey	RCTGMCJBQGBLKT-UHFFFAOYSA-N
SMILES	Cc1ccccc1N=Nc1ccc(N=Nc2c(O)ccc3ccccc23)c(C)c1
Water Solubility	Insoluble in water; soluble in benzene, methanol, acetone, isopropanol; slightly soluble in ethanol

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL5775000

CHEMICAL NAME :: 2-Naphthol, 1-((4-(o-tolylazo)-o-tolyl)azo)-

CAS REGISTRY NUMBER :: 85-83-6

BEILSTEIN REFERENCE NO. :: 0709018

LAST UPDATED :: 199701

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C24-H20-N4-O

MOLECULAR WEIGHT :: 380.48

WISWESSER LINE NOTATION :: L66J BNUNR B1 DNUNR B1&& CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 512 mg/kg/58W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - hamster Embryo

DOSE/DURATION :: 100 mg/L

REFERENCE :: AETODY Advances in Modern Environmental Toxicology. (Senate Press, Inc., P.O. Box 252, Princeton Junction, NJ 08550) V.1- 1980- Volume(issue)/page/year: 1,241,1980 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,217,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,217,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1356 No. of Facilities: 212 (estimated) No. of Industries: 6 No. of Occupations: 13 No. of Employees: 2432 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1356 No. of Facilities: 1210 (estimated) No. of Industries: 15 No. of Occupations: 23 No. of Employees: 20219 (estimated) No. of Female Employees: 10256 (estimated)

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;T: Toxic;
Risk Phrases	R36/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	QL5775000
HS Code	2927000090

Customs

HS Code	2927000090
Summary	2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles25

Determination of banned 10 azo-dyes in hot chili products by gel permeation chromatography-liquid chromatography-electrospray ionization-tandem mass spectrometry.

J. Chromatogr. A. 1164(1-2) , 120-8, (2007)

An accurate method based on the use of gel permeation chromatography (GPC)-liquid chromatography-tandem mass spectrometry interfaced with electrospray ionization (GPC-LC-ESI-MS/MS) was devised for the...

Development and validation of a confirmatory HPLC method for simultaneous determination of Sudan dyes in animal tissues and eggs.

J. Chromatogr. Sci. 48(1) , 63-7, (2010)

A simple and sensitive high-performance liquid chromatography (HPLC) analytical method for the simultaneous determination of six Sudan dyes (Sudan Red G, Sudan I, Sudan II, Sudan III, Sudan Red 7B, Su...

Analysis and testing of biological stains--the Biological Stain Commission Procedures.

Biotech. Histochem. 77(5&6) , 237-275, (2002)

Synonyms

1-({2-Methyl-4-[(2-methylphenyl)diazenyl]phenyl}diazenyl)-2-naphthol

o-Tolylazo-o-tolylazo-β-naphthol

Scarlet Red

2-Naphthalenol, 1-[(E)-2-[2-methyl-4-[(E)-2-(2-methylphenyl)diazenyl]phenyl]diazenyl]-

EINECS 201-635-8

solvent red percent24

1-[(E)-{2-Methyl-4-[(E)-(2-methylphenyl)diazenyl]phenyl}diazenyl]-2-naphthol

fatredb

AKA501

1-[(E)-{2-methyl-4-[(E)-(2-methylphenyl)diazenyl]phenyl}diazenyl]naphthalen-2-ol

Solvent Red 24

MFCD00003893

c.i.258

oilredf

2-Naphthalenol, 1-[2-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl]diazenyl]-

oilredd

2-Naphthol, 1-[[4-(o-tolylazo)-o-tolyl]azo]-

oilreda

L66J BNUNR B1 DNUNR B1&& CQ

o-Tolylazo-o-tolylazo-b-naphthol

C.I. Solvent Red 24 (8CI)

oilred3

1-[[2-Methyl-4-[(2-methylphenyl)azo]phenyl]azo]-2-naphthalenol

2-Naphthalenol, 1-[[2-methyl-4-[(2-methylphenyl)azo]phenyl]azo]-

2-NAPHTHALENOL, 1-((2-METHYL-4-((2-METHYLPHENYL)AZO)PHENYL)AZO)-

sudanp

1-{[2-Methyl-4-(o-tolylazo)phenyl]azo}naphthalen-2-ol

oilred7

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CAS 85-83-6 | Sudan IV

Names

Sudan IV BiologicalActivity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Customs

Articles25

Synonyms

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