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CAS 99-55-8 | 2-Methyl-5-nitroaniline

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Common Name2-Methyl-5-nitroaniline
CAS Number99-55-8Molecular Weight152.151
Density1.3±0.1 g/cm3Boiling Point329.4±22.0 °C at 760 mmHg
Molecular FormulaC7H8N2O2Melting Point103-106 °C(lit.)
MSDSChineseUSAFlash Point153.0±22.3 °C
Symbol
GHS06, GHS08
Signal WordDanger

Names

Name5-nitro-o-toluidine
SynonymMore Synonyms

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point329.4±22.0 °C at 760 mmHg
Melting Point103-106 °C(lit.)
Molecular FormulaC7H8N2O2
Molecular Weight152.151
Flash Point153.0±22.3 °C
Exact Mass152.058578
PSA71.84000
LogP1.83
Vapour Pressure0.0±0.7 mmHg at 25°C
Index of Refraction1.616
InChIKeyDSBIJCMXAIKKKI-UHFFFAOYSA-N
SMILESCc1ccc([N+](=O)[O-])cc1N
Storage condition2-8°C
StabilityStable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, acids, chloroformates.
Water Solubility<0.1 g/100 mL at 19 ºC

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XU8225000
CHEMICAL NAME :
o-Toluidine, 5-nitro-
CAS REGISTRY NUMBER :
99-55-8
BEILSTEIN REFERENCE NO. :
0879021
LAST UPDATED :
199701
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C7-H8-N2-O2
MOLECULAR WEIGHT :
152.17
WISWESSER LINE NOTATION :
ZR B1 ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 gm/kg/78W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - mouse Embryo
DOSE/DURATION :
160 ug/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12,21,1988 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,169,1990 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,169,1990 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Carcinogen JAN 1993 OEL-SWITZERLAND;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1540 No. of Facilities: 41 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 13741 (estimated) No. of Female Employees: 12621 (estimated)

Safety Information

Symbol
GHS06, GHS08
Signal WordDanger
Hazard StatementsH301-H311-H331-H351-H412
Precautionary StatementsP261-P273-P280-P301 + P310-P311
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard CodesT:Toxic
Risk PhrasesR23/24/25;R40;R52/53
Safety PhrasesS36/37-S45-S61
RIDADRUN 2660 6.1/PG 3
WGK Germany3
RTECSXU8225000
Packaging GroupIII
Hazard Class6.1
HS Code2921430090

Customs

HS Code2921430090
SummaryHS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles6

More Articles
5-Nitro-ortho-toluidine.

IARC Monogr. Eval. Carcinog. Risks Hum. 48 , 169-77, (1990)

Liver dysfunction among workers handling 5-nitro-o-toluidine.

Gut 50(2) , 266-70, (2002)

5-Nitro-o-toluidine is an aromatic nitro amino compound. While other aromatic compounds are known to damage the human liver and are registered as toxic substances, toxicity information concerning 5-ni...

Establishment of an extraction method for the recovery of tattoo pigments from human skin using HPLC diode array detector technology.

Anal. Chem. 78(18) , 6440-7, (2006)

Tattooing is a widespread process of puncturing pigments into skin, whereas the resulting concentration inside the skin remains unknown. Many tattoo colorants are organic pigments, such as azo pigment...

Synonyms

Benzenamine, 2-methyl-5-nitro-
EINECS 202-765-8
5-Nitro-o-toluidine
2-methyl-5-nitrophenylamine
2-Methyl-5-nitrobenzolamin
PNOT
2-Methyl-5-nitroaniline
ScarletbaseG
2-Amino-4-nitrotoluene
devolscarletb
2-Amino-1-methyl-4-nitrobenzene
4-nitro-2-amino-toluene
fastscarletg
2-Methyl-5-nitrobenzenamine
ZR B1 ENW
MFCD00007741

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