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7-ISOPROPYLISATIN | CAS 57816-97-4

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7-ISOPROPYLISATIN Basic information

Product Name:7-ISOPROPYLISATIN
Synonyms:7-ISOPROPYLISATIN;UKRORGSYN-BB BBV-030970;1H-Indole-2,3-dione, 7-(1-methylethyl)-;7-Isopropylindoline-2,3-dione;7-(1-Methylethyl)-1H-indole-2,3-dione
CAS:57816-97-4
MF:C11H11NO2
MW:189.21
EINECS:
Product Categories:
Mol File:57816-97-4.mol

7-ISOPROPYLISATIN Chemical Properties

Melting point 196-198 °C(Solv: dichloromethane (75-09-2))
density 1.200±0.06 g/cm3(Predicted)
pka9.81±0.20(Predicted)
InChIInChI=1S/C11H11NO2/c1-6(2)7-4-3-5-8-9(7)12-11(14)10(8)13/h3-6H,1-2H3,(H,12,13,14)
InChIKeyXWJSENVAAAAHBN-UHFFFAOYSA-N
SMILESN1C2=C(C=CC=C2C(C)C)C(=O)C1=O

Safety Information

MSDS Information

7-ISOPROPYLISATIN Usage And Synthesis

Synthesis
Uses7-Isopropyl-1H-indole-2,3-dione is used in the synthetic preparation of 2-aminoquinazoline derivatives as PLK1 inhibitor useful in treatment of various diseases.
To concentrated sulfuric acid at 80° C. was added 2-hydroxyimino-N-(2-isopropyl-phenyl)-acetamide in several small portions over 10 minutes. After addition it was heated at 80° C. for 30 minutes., then poured into ice. Filtration, washing with water, and drying under vacuum over P2O5 provided 2.974 g (84%) of 7-Isopropyl-1H-indole-2,3-dione as a solid. 

7-ISOPROPYLISATIN Preparation Products And Raw materials

Declaration: The products displayed on this website are intended exclusively for industrial applications or scientific research. They are not intended for medical, pharmaceutical, or food use. In accordance with applicable laws and regulations, purchasing organizations must hold valid qualifications and approvals.

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